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Invitrogen™ Caspase 6 Monoclonal Antibody (MCH2 14 1-190)
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Catalog No. 01674344
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100 μg
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Catalog No. Quantity
01-674-344 100 μg
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Catalog No. 01-674-344 Supplier Invitrogen™ Supplier No. MA112558
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Description

Mouse Monoclonal Antibody

A suggested positive control for this product is MCF-7 cell lysate.

Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Caspase 6
Applications Western Blot
Classification Monoclonal
Clone MCH2 14 1-190
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.08% sodium azide
Gene Casp6
Gene Accession No. P55212
Gene Alias apoptotic protease MCH-2; CASP6; CASP-6; caspase 6; caspase 6, apoptosis-related cysteine peptidase; caspase 6, apoptosis-related cysteine protease; caspase-6; Caspase-6 subunit p11; Caspase-6 subunit p18; mCASP-6; MCH2
Gene Symbols Casp6
Host Species Mouse
Immunogen Recombinant human capase-6 protein.
Purification Method Protein A/G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 839
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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