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Invitrogen™ Caspase 9 (Cleaved Asp330) Recombinant Rabbit Monoclonal Antibody (HL3858)
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Catalog No. MA566168
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MA566168 100 μL
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Catalog No. MA566168 Supplier Invitrogen™ Supplier No. MA566168
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Rabbit Recombinant Monoclonal Antibody

Caspase 9 (Cleaved Asp330) Recombinant Monoclonal Antibody for Western Blot

Caspase 9 (Cleaved Asp330) encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Caspase 9 (Cleaved Asp330)
Applications Western Blot
Classification Recombinant Monoclonal
Clone HL3858
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene CASP9
Gene Accession No. P55211
Gene Alias 25 kDa caspase-9 dominant negative protein; APAF3; APAF-3; apoptotic protease activating factor 3; apoptotic protease MCH-6; Apoptotic protease-activating factor 3; CASP9; CASP-9; Casp9_v1; Casp-9-CTD; caspase 9; caspase 9, apoptosis-related cysteine peptidase; caspase-9; caspase-9 dominant negative form; Caspase-9 subunit p10; Caspase-9 subunit p35; caspase-9-carboxyl-terminal divergent; ICE-LAP6; ICE-like apoptotic protease 6; MCH6; PPP1R56; protein phosphatase 1, regulatory subunit 56
Gene Symbols CASP9
Host Species Rabbit
Immunogen Synthetic peptide of human Caspase 9 (cleaved Asp330).
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 842
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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