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β-Catenin Rabbit Polyclonal Antibody, Epredia™

Catalog No. p-4539343 Shop All Epredia Products
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100 μL
500 μL
1 mL
Form:
Concentrated
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RB9035P0 100 μL Concentrated
RB9035P1 500 μL Concentrated
RB9035P 1 mL Concentrated
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Catalog No. RB9035P0 Supplier Epredia Supplier No. RB9035P0

Description

Stain formalin-fixed, paraffin-embedded tissues with Epredia™ Catenin, β, Rabbit Polyclonal Antibody.

The catenins (α, Β and γ) are ubiquitously expressed cytoplasmic proteins associated with E-cadherin at cellular junctions. Β-catenin also binds to N-cadherin and co-immunoprecipitates with APC. Cadherin/catenin complexes are linked to the cytoskeleton via a direct association between α-actinin and α-catenin. Increased tyrosine phosphorylation can disrupt catenin-cadherin complexes, influencing cellular adhesion.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human and Mouse. Others not tested.

Epitope: C-terminal

Immunogen: A synthetic peptide from the C-terminus of the β-catenin protein

Molecular Weight: 92kDa

Positive Control: MCF-7 cells, Breast CA

Cellular Localization: Cytoplasmic and cell membrane

This antibody is excellent for staining of formalin-fixed, paraffin-embedded tissues.

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation

Specifications

Antigen Catenin, beta
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 200µg/mL
Conjugate Unconjugated
Host Species Rabbit
Immunogen A synthetic peptide from the C-terminus of the beta-catenin protein
Quantity 100 μL
Regulatory Status IVD
Research Discipline Transcription Regulation
Primary or Secondary Primary
Target Species Human
Form Concentrated
Isotype IgG
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