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Abcam CAY10585, HIF-1alpha Inhibitor, Solid, 5 mg

Catalog No. 502705759
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50-270-5759 5 mg
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Catalog No. 50-270-5759 Supplier Abcam Supplier No. AB1444225MG
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Potent HIF-1α inhibitor with >97% purity that suppresses transcription of target genes VEGF and erythropoietin.

  • Molecular Weight: 435.5 Da
  • Purity: >97%
  • Mechanism: HIF-1α inhibitor (IC50 values are 2.6 μM for Hep3B and 0.7 μM for AGS cell lines)
  • Biological activity: Suppresses transcription of HIF-1 target genes VEGF and erythropoietin at 10 μM; attenuates hypoxia-induced ANP secretion; blunts BMP9-induced osteogenic signaling in MSCs
  • Form: Solid

Specifications

Shipping Condition Ambient
Target Molecule HIF-1α
Substrate Properties Chemical Substrate
Alternate Part Number CAY10585
Content And Storage Store at -20°C.
Form Solid
Quantity 5 mg
For Use With (Application) HIF-1α inhibition, transcription suppression, osteogenic signaling inhibition
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