Invitrogen™ CBX6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5114950

Catalog No. PIPA5114950

Description

Antibody detects endogenous levels of total CBX6.

Polycomb group (PcG) proteins form multiprotein complexes that regulate expression patterns of developmental and cell proliferation genes. CBX6 (chromobox protein homolog 6) is a 412 amino acid protein that is a component of the chromatin-associated PcG complex. Through interaction with PcG, CBX6 modifies chromatin and maintains the transcriptionally repressive state of genes. Members of the chromobox domain protein family are characterized by the presence of a 37 amino acid chromobox (CHRromatin Organization MOdifier) domain. This domain plays a mechanistic role in targeting chromodomain proteins to specific regions of the nucleus.

Specifications

• Antigen: CBX6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CBX6
• Gene Alias: CBX6; chromobox 6; chromobox homolog 6; chromobox protein homolog 6; chromobox-like protein 6
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23466, 315136, 494448
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: O95503, Q9DBY5
• Gene Symbols: CBX6
• Immunogen: A synthesized peptide derived from human CBX6(Accession O95503), corresponding to amino acid residues M1-I48.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG