Invitrogen™ CBX8 Monoclonal Antibody (8G7)

Catalog No.	Quantity
PIMA549285	100 μg

Catalog No. PIMA549285 Supplier Invitrogen™ Supplier No. MA549285

Description

Mouse Monoclonal Antibody

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL. Positive Control - WB: human Hela whole cell, human A549 whole cell, human Raji whole cell. IHC: human gallbladder adenocarcinoma tissue. Flow: HL-60 cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

Specifications

• Antigen: CBX8
• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: 8G7
• Concentration: 500 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 4mg trehalose and no preservative
• Gene: CBX8
• Gene Accession No.: Q9HC52
• Gene Alias: CBX8; chromobox 8; chromobox homolog 8; chromobox homolog 8 (Pc class homolog, Drosophila); chromobox protein homolog 8; HPC3; mPc3; Pc class 3 homolog; Pc3; polycomb 3; polycomb 3 homolog; RC1; rectachrome 1
• Gene Symbols: CBX8
• Host Species: Mouse
• Immunogen: E.coli-derived human Cbx8 recombinant protein (Position: M1-R389).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 57332
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG2b