CCDC99 Rabbit anti-Human, Polyclonal, Proteintech

Catalog No.	Quantity
50-173-4490	150 μL

Catalog No. 50-173-4490 Supplier Proteintech Group Inc Supplier No. 246891AP150UL

Description

Rabbit Polyclonal Antibody

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridizations indicate that this lectin is specifically expressed in keratinocytes. It is expressed at all stages of epidermal differentiation (i.e., in basal and suprabasal layers). The protein was found mainly in stratified squamous epithelium. It is moderately repressed by retinoic acid. The antigen localized to basal keratinocytes, although it was also found at lower levels in the suprabasal layers, where it concentrated to areas of cell-to-cell contact. The cellular localization and its striking down-regulation in cultured keratinocytes imply a role in cell-cell and/or cell-matrix interactions necessary for normal growth control.

Specifications

• Antigen: CCDC99
• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Classification: Polyclonal
• Concentration: 0.28 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: SPDL1
• Gene Accession No.: Q96EA4
• Gene Alias: CCDC99, hSpindly, MU-RMS-40.4A, Protein Spindly, spdly
• Gene Symbols: SPDL1
• Host Species: Rabbit
• Immunogen: CCDC99 Fusion Protein Ag20430
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 54908
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG