Invitrogen™ CCL21 Monoclonal Antibody (59106)

Rat Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIMA523755	Invitrogen™ MA523755	500 μg
PIMA523837	Invitrogen™ MA523837	100 μg

Description

This antibody does not cross-react with recombinant human (rh) 6Ckine, rhMIP-1 alpha, rhMIP-1 beta, recombinant mouse (rm) MIP-1 alpha, rmMIP-1 beta, rhMIP-1 gamma, rmMIP-1 gamma, rmMIP-2, rhMIP-3 alpha, rmMIP-3 alpha, rhMIP-3 beta, rmMIP-3 beta, rhTeck, or rmTeck. Reconstitute at 0.5 mg/mL in sterile PBS.

This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 (CCR7) that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19).

Specifications

• Antigen: CCL21
• Concentration: 0.5 mg/mL
• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Western Blot
• Conjugate: Unconjugated
• Host Species: Rat
• Regulatory Status: RUO
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: P84444, P86792, P86793
• Gene ID (Entrez): 100042493, 18829, 65956
• Immunogen: E. coli-derived recombinant mouse CCL21/6Ckine Ser24-Gly133.
• Product Type: Antibody

• Clone: 59106
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Classification: Monoclonal
• Form: Lyophilized
• Isotype: IgG2b
• Target Species: Mouse
• Gene: Ccl21b
• Gene Alias: 6 Ckine; 6CKBAC1; 6CKBAC2; 6Ckine; AI159701; ALP; AW987545; beta chemokine exodus-2; beta-chemokine exodus-2; CC chemokine 6Ckine-ser; C-C motif chemokine 21; C-C motif chemokine 21a; C-C motif chemokine 21b; C-C motif chemokine 21c; C-C motif chemokine ligand 21; CCL21; Ccl21a; Ccl21b; Ccl21c; Ccl21-leu; CCL21-Ser; chemokine (C-C motif) ligand 21; chemokine (C-C motif) ligand 21A (serine); chemokine (C-C motif) ligand 21B (leucine); chemokine (C-C motif) ligand 21b (serine); chemokine (C-C motif) ligand 21C (leucine); chemokine CCL21/6CKINE; CKb9; ECL; Efficient Chemoattractant for Lymphocytes; exodus-2; plt; Scya21; SCYA21a; Scya21b; Scya21c; secondary lymphoid organ chemokine; secondary lymphoid tissue chemokine; Secondary lymphoid-tissue chemokine; SLC; small inducible cytokine A21; small inducible cytokine A21a; small inducible cytokine A21c; small inducible cytokine subfamily A (Cys-Cys), member 21; small-inducible cytokine A21; Small-inducible cytokine A21a; Small-inducible cytokine A21b; Small-inducible cytokine A21c; TCA4; Thymus-derived chemotactic agent 4; UNQ784/PRO1600
• Gene Symbols: Ccl21a, Ccl21b, Ccl21c
• Primary or Secondary: Primary
• Purification Method: Protein A/G