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Invitrogen™ CCR1 Monoclonal Antibody (8E10G6)
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Catalog No. PIMA531671
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100 μL
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Catalog No. Quantity
PIMA531671 100 μL
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Catalog No. PIMA531671 Supplier Invitrogen™ Supplier No. MA531671
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Description

Mouse Monoclonal Antibody

Amino acid sequence of the immunogen is proprietary. This antibody has been tested in indirect ELISA.

Chemokines play important roles in inflammation and are critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors. The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines. One of the CCR receptors, CCR1, is expressed on neutrophils, monocytes, lymphocytes, and eosinophils and binds the leukocyte chemoattractant and hemopoiesis regulator macrophage-inflammatory protein (MIP-1 ), eotaxin, as well as several other related chemokines. Mice lacking the chemokine receptor CCR1 have defects in neutrophil trafficking and proliferation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CCR1
Applications ELISA, Flow Cytometry, Western Blot
Classification Monoclonal
Clone 8E10G6
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene CCR1
Gene Accession No. P32246
Gene Alias C-C chemokine receptor type 1; C-C CKR-1; C-C motif chemokine receptor 1; CC-CKR-1; Ccr1; CCR-1; CD191; chemokine (C-C motif) receptor 1; chemokine (C-C) receptor 1; CKR1; CKR-1; CMKBR1; CMKR1; HM145; LD78 receptor; macrophage inflammatory protein 1-alpha receptor; macrophage inflammatory protein-1 alpha receptor; MIP-1 alpha R; MIP-1 alphaR; MIP-1alpha-R; MIP1aR; Mip-1a-R; RANTES receptor; RANTES-R; SCYAR1
Gene Symbols CCR1
Host Species Mouse
Immunogen Purified recombinant fragment of human CD191 expressed in E. coli.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1230
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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