Invitrogen™ CCR10 Polyclonal Antibody

Catalog No.	Quantity
PI720308	100 μg

Catalog No. PI720308 Supplier Invitrogen™ Supplier No. 720308

Description

Rabbit Polyclonal Antibody

These Polyclonal antibodies are of rabbit origin developed by immunizing animals with proteins or peptides. The polyclonal antibody is purified by affinity purification from the rabbit sera generated after immunizing the rabbits with a specific type of protein or peptide. The purified antibody is tested for its functionality in various relevant research applications. The antibody is developed for Research Use Only and is non-hazardous or non-infectious in nature. This antibody is predicted to react with Monkey, Bovine and Rabbit.

Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27; CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation.

Specifications

• Antigen: CCR10
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.4
• Gene: CCR10
• Gene Accession No.: P46092, Q9JL21
• Gene Alias: CC chemokine receptor 10; C-C chemokine receptor type 10; C-C CKR-10; C-C motif chemokine receptor 10; CC-CKR-10; CCR10; CCR-10; chemokine (C-C motif) receptor 10; chemokine C-C receptor 9; Cmkbr9; G protein-coupled receptor 2; Gpr2; G-protein coupled receptor 2; MGC151420; RP23-281C18.3
• Gene Symbols: CCR10
• Host Species: Rabbit
• Immunogen: Peptides corresponding to Human CCR10 (aa 14-29, 350-362).
• Purification Method: Affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 12777, 2826
• Target Species: Human, Mouse
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov