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Invitrogen™ CCR9 Chimeric Recombinant Rabbit Monoclonal Antibody (9B1)
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Catalog No. PIMA548297
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200 μg
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PIMA548297 200 μg
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Catalog No. PIMA548297 Supplier Invitrogen™ Supplier No. MA548297
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Rabbit Recombinant Monoclonal Antibody

Specificity: 9B1 antibody recognizes CCR9 at the N-terminus. CCR9 is a member of the G protein coupled receptor family and is involved in T cell development in the thymus and in gut-associated immune response. Mouse CCR9 is highly expressed on different stages of thymocytes and upregulated on CD4+CD8+ cells.

The protein encoded by this gene is a member of the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are key regulators of the thymocytes migration and maturation in normal and inflammation conditions. The specific ligand of this receptor is CCL25. It has been found that this gene is differentially expressed by T lymphocytes of small intestine and colon, suggested a role in the thymocytes recruitment and development that may permit functional specialization of immune responses in different segment of the gastrointestinal tract. This gene is mapped to the chemokine receptor gene cluster region. Two alternatively spliced transcript variants have been described.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CCR9 Chimeric
Applications Flow Cytometry, Neutralization, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 9B1
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% ProClin 300
Gene Ccr9
Gene Accession No. Q9WUT7
Gene Alias A130091K22Rik; C-C chemokine receptor type 9; C-C CKR-9; C-C motif chemokine receptor 9; CC-CKR-9; Ccr9; CCR-9; CDw199; CDw199 antigen; chemokine (C-C motif) receptor 9; chemokine C-C receptor 10; Cmkbr10; G protein-coupled receptor 28; GPR28; GPR-9-6; G-protein coupled receptor 28
Gene Symbols Ccr9
Host Species Rabbit
Immunogen This antibody was raised by immunizing rats with KLH-conjugated linear peptide corresponding to the N-terminus of mouse CCR9.
Purification Method Protein A
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12769
Target Species Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG κ
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