Invitrogen™ CD1 Monoclonal Antibody (20.27)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA528265

Catalog No. PIMA528265

Description

This antibody recognizes the ovine CD1 cell surface antigen. CD1 is primarily expressed in cortical thymocytes and dendritic cells in the dermis, afferent lymph, lymph node, spleen and thymus.

The CD1 is a family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: CD1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.09% sodium azide
• Gene Accession No.: 0
• Gene Symbols: LOC101111409
• Immunogen: Ovine thymocytes.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Sheep
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, Immunocytochemistry
• Clone: 20.27
• Conjugate: Unconjugated
• Gene: LOC101111409
• Gene Alias: CD1; CD1 antigen; CD1.1; CD1A; CD1A antigen, a polypeptide; CD1a molecule; cd1a1; CD1A1 antigen; CD1c; cluster of differentiation 1 A; cortical thymocyte antigen CD1A; differentiation antigen CD1-alpha-3; epidermal dendritic cell marker CD1a; FCB6; HTA1; hTa1 thymocyte antigen; LOC101111409; R4; T6; T-cell surface antigen T6/Leu-6; T-cell surface glycoprotein CD1a
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 101111409
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid