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  6. Epredia™ Lab Vision™ CD106/VCAM-1 Ab-3 Mouse Monoclonal Antibody, 200μg/mL, BSA and azide

Epredia™ Lab Vision™ CD106/VCAM-1 Ab-3 Mouse Monoclonal Antibody, 200μg/mL, BSA and azide

Catalog No. p-4547009 Shop All Epredia Products
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1 mL
Form:
Prediluted
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MS1101R1 1 mL Prediluted
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Catalog No. MS1101R1 Supplier Epredia™ Supplier No. MS1101R1

Description

Ensure accurate, reproducible results in immunohistochemistry and western blotting experiments with Epredia™ CD106/VCAM-1 Ab-3, Mouse Monoclonal Antibody.

CD106 (also known as vascular cell adhesion molecule-1 [VCAM-1] and INCAM-110) is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine-stimulated vascular endothelial cells, and at minimal levels on unstimulated endothelial cells. It is also present on follicular and interfollicular dendritic cells of lymph nodes, myoblasts, and some macrophages. CD106 serves as a ligand for leukocyte integrin alphaBeta (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in tumor metastasis.

Host Species: Mouse

Clone: 1.4C3

Isotype: IgG1

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Stimulated human umbilical vein endothelial cells (HUVEC)

Molecular Weight: 110 kDa

Positive Control: Placenta

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Frozen and formalin/paraffin)
  • Western Blotting (Not recommended)

Note:

USA: RUO; Int'l: RUO

General References:

1. Thornhill M, et. al. (1990) J Immunol, 145:865.

2. Wellicome s M, et. al. (1990) J Immunol, 144:2558.

3. Kyan-Aung U, et. al. (1991) J Immunol, 146:521-528

4. Burrows f J, et. al. Cancer Res, 51:4768.

5. Osborne L, et al. (1994) J Cell Biol, 124:601.

6. Thornhill M, et. al. (1991) J Immunol, 146:592.

Specifications

Antigen CD106/VCAM-1 Ab-3
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone 1.4C3
Conjugate Unconjugated
Formulation Ready-to-use for IHC (UVLP)
Host Species Mouse
Immunogen Stimulated human umbilical vein endothelial cells (HUVEC)
Quantity 1 mL
Regulatory Status RUO
Research Discipline Inflammation
Primary or Secondary Primary
Target Species Human
Form Prediluted
Isotype IgG1
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