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Invitrogen™ CD11c Monoclonal Antibody (FK24)
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Catalog No. 01676911
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01-676-911 1 mL
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Catalog No. 01-676-911 Supplier Invitrogen™ Supplier No. MA135070
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Description

Mouse Monoclonal Antibody

The antibody reacts with the alpha chain the 150 kD molecule of the CD11c/CD18 Integrin complex (g150/95) which is expressed on monocytes and in a lower density on granulocytes and NK-cells of peripheral blood. It also reacts with many myelomonocytic and monocytic leukemias and (weakly) with part of the T8 positive cells (OKM1-like). The Integrins are important molecules in cellular adhesion and cellular interactions. Positive controle perifere blood lymphocytes.

CD11, along with CD18, form a heterodimer adhesion molecule. In particular, CD11 is composed of CD11a, CD11b and CD11c. CD11a is a leukocyte marker that is expressed in B and T lymphocytes, macrophages, monocytes, neutrophils, basophils and eosinophils. CD11b is primarily expressed by monocytes, macrophages, natural killer cells, some B and T-cells, and granulocytes. CD11c is expressed in monocytes, macrophages, natural killer cells, some granulocytes and less so in a subset of lymphocytes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD11c
Applications Immunocytochemistry
Classification Monoclonal
Clone FK24
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation PBS with 0.1% BSA and 0.02% sodium azide
Gene Itgax
Gene Accession No. P20702
Gene Alias AI449405; CD11 antigen-like family member C; CD11c; CD11C (p150) alpha polypeptide; complement component 3 receptor 4 subunit; complement receptor 4; Cr4; integrin alpha X; integrin alpha-X; integrin aX; integrin subunit alpha X; integrin, alpha X; integrin, alpha X (antigen CD11C (p150), alpha polypeptide); integrin, alpha X (complement component 3 receptor 4 subunit); Itgax; Leu M5; leu M5, alpha subunit; leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; leukocyte surface antigen p150,95, alpha subunit; myeloid membrane antigen, alpha subunit; N418; p150 95 integrin alpha chain; RGD1561123; SLEB6
Gene Symbols Itgax
Host Species Mouse
Immunogen AML-blasts.
Quantity 1 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3687
Target Species Human
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG1
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Safety and Handling

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