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Description
The B-ly6 monoclonal antibody specifically binds to the 150 kDa adhesion glycoprotein CD11c (p150, integrin α chain). CD11c is expressed on dendritic cells, monocytes, macrophages, granulocytes, NK cells and subsets of B and T cells. It associates with CD18 to form the CD11c/CD18 complex that binds fibrinogen and has been reported to be a receptor for iC3b and ICAM-1. Reports indicate that CD11c/CD18 plays a role as an adhesion molecule that mediates cellular binding to ligands expressed on stimulated epithelium and endothelium.
Specifications
Specifications
| Antigen | CD11c |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | B-ly6 |
| Conjugate | R718 |
| Host Species | Mouse |
| Quantity | 100 Tests |
| Regulatory Status | RUO |
| Primary or Secondary | Primary |
| Target Species | Human |
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