Invitrogen™ CD133 (Prominin-1) Recombinant Rabbit Monoclonal Antibody (BLR093G)

Catalog No.	Quantity
PIMA544377	100 μL
PIMA544378	10 μL

Catalog No. PIMA544377

Supplier: Invitrogen™ MA544377

Description

Rabbit Recombinant Monoclonal Antibody

Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections.

The CD133 (AC133) antigen is a 97 kDa glycoprotein, with 5 transmembrane domains, that shows up as a 120 kDa band on protein gels due to glycosylation. CD133 is a cell surface marker expressed by immature hematopoietic stem cells but not mature blood cells. In addition to hematopoietic stem and progenitor cells, CD133 has been found to be a marker for other stem and progenitor cells including neural and embryonic stem cells. CD133 has been shown to be expressed in cancers, including some leukemias and brain tumors, that may be derived from stem cells. Low level expression could also be detected in the kidney, pancreas, placenta, and fetal liver. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of the CD133 gene is also associated with several types of cancer. CD133 is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner, and multiple transcript variants encoding different isoforms have been found.

Specifications

• Antigen: CD133 (Prominin-1)
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Recombinant Monoclonal
• Clone: BLR093G
• Concentration: 0.25 mg/mL
• Conjugate: Unconjugated
• Formulation: BBS with 0.1% BSA and 0.09% sodium azide; pH 8.2
• Gene: PROM1
• Gene Accession No.: O43490
• Gene Alias: 4932416E19Rik; AC133; Antigen AC133; antigen AC133 homolog; antigen CD133; CD107b; CD133; CORD12; fudenine; hematopoietic stem cell antigen; hProminin; Lamp II; Lamp2; LAMP-2; Lamp-2a; Lamp-2b; Lamp-2c; LGP-96; LGP-B; Mac3; MCDR2; MSTP061; Prom; PROM1; Prom-1; prominin 1; prominin 1.s1; Prominin1; prominin-1; prominin-1.s2; prominin-like 1; prominin-like protein 1; PROML1; RP41; STGD4
• Gene Symbols: PROM1
• Host Species: Rabbit
• Immunogen: Peptide representing a region between residue 350 and 400 of Human prominin-1 (CD133).
• Purification Method: Purified
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 8842
• Target Species: Human
• Content And Storage: 4°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG