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Invitrogen™ CD133 Recombinant Rabbit Monoclonal Antibody (HL1631)
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Catalog No. MA556638
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MA556638 100 μL
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Catalog No. MA556638 Supplier Invitrogen™ Supplier No. MA556638
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Description

Rabbit Recombinant Monoclonal Antibody

CD133 Recombinant Monoclonal Antibody for Flow

The CD133 (AC133) antigen is a 97 kDa glycoprotein, with 5 transmembrane domains, that shows up as a 120 kDa band on protein gels due to glycosylation. CD133 is a cell surface marker expressed by immature hematopoietic stem cells but not mature blood cells. In addition to hematopoietic stem and progenitor cells, CD133 has been found to be a marker for other stem and progenitor cells including neural and embryonic stem cells. CD133 has been shown to be expressed in cancers, including some leukemias and brain tumors, that may be derived from stem cells. Low level expression could also be detected in the kidney, pancreas, placenta, and fetal liver. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of the CD133 gene is also associated with several types of cancer. CD133 is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner, and multiple transcript variants encoding different isoforms have been found.
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Specifications

Antigen CD133
Applications Flow Cytometry
Classification Recombinant Monoclonal
Clone HL1631
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene PROM1
Gene Accession No. O43490
Gene Alias 4932416E19Rik; AC133; Antigen AC133; antigen AC133 homolog; antigen CD133; CD107b; CD133; CORD12; fudenine; hematopoietic stem cell antigen; hProminin; Lamp II; Lamp2; LAMP-2; Lamp-2a; Lamp-2b; Lamp-2c; LGP-96; LGP-B; Mac3; MCDR2; MSTP061; Prom; PROM1; Prom-1; prominin 1; prominin 1.s1; Prominin1; prominin-1; prominin-1.s2; prominin-like 1; prominin-like protein 1; PROML1; RP41; STGD4
Gene Symbols PROM1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the Extracellular domain of human CD133. The exact sequence is proprietary.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8842
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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