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CD14 Mouse anti-Baboon, Cynomolgus, Human, Rhesus, Brilliant Ultraviolet 737, Clone: M5E2, BD Horizon™

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 612763

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Catalog No. BDB612763


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Description

Description

The M5E2 monoclonal antibody specifically binds to CD14, a 53–55 kDa glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein expressed at high levels on monocytes. Additionally, the anti-CD14 antibody reacts with interfollicular macrophages, reticular dendritic cells, and some Langerhans cells. CD14 has been identified as a high affinity cell-surface receptor for complexes of lipopolysaccharide (LPS) and serum LPS-binding protein, LPB.

The antibody was conjugated to BD Horizon™ BUV737 which is part of the BD Horizon Brilliant™ Ultraviolet family of dyes. This dye is a tandem fluorochrome of BD Horizon BUV395 with an Ex Max of 348-nm and an acceptor dye with an Em Max at 737-nm. BD Horizon Brilliant BUV737 can be excited by the ultraviolet laser (355 nm) and detected with a 740/35 filter. Due to the excitation of the acceptor dye by other laser lines, there may be significant spillover into channels detecting Alexa Fluor™ 700-like dyes (e.g., 712/20-nm filter).

Specifications

Specifications

CD14
M5E2
Aqueous buffered solution containing ≤0.09% sodium azide.
Mouse
IgG2a, κ
100 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Flow Cytometry
Brilliant Ultraviolet 737
Affinity Purified
Human CD14 Protein
Affinity Chromatography
RUO
Primary
Baboon, Cynomolgus, Human, Rhesus Monkey
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