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Invitrogen™ CD142 Monoclonal Antibody (K06319_4H12), Invitrogen™

Catalog No. MA556353
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200 μL
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MA556353 200 μL
MA555973 50 μL
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Catalog No. MA556353 Supplier Invitrogen™ Supplier No. MA556353
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Mouse Monoclonal Antibody

Sequence of this protein is as follows: LTDEIVKDVK QTYLARVFSY PAGNVESTGS AGEPLYENSP EFTPYLETNL GQPTIQSFEQ VGTKVNVTVE

This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD142
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone K06319_4H12
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.5% BSA and 0.09% sodium azide
Gene F3
Gene Accession No. P13726
Gene Alias AA409063; CD142; Cf3; Cf-3; Coagulation factor III; coagulation factor III (thromboplastin, tissue factor); coagulation factor III, tissue factor; F3; TF; TFA; Thromboplastin; Tissue factor
Gene Symbols F3
Host Species Mouse
Immunogen Recombinant human F3 (immunogen range is 91-160).
Purification Method Protein A
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2152
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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