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Invitrogen™ CD142 Monoclonal Antibody (TF9-10H10)
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Catalog No. MA183495
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100 μg
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MA183495 100 μg
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Catalog No. MA183495 Supplier Invitrogen™ Supplier No. MA183495
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Description

Mouse Monoclonal Antibody

This antibody does not react with rabbit. Mouse anti Human CD142 antibody, clone TF9-10H10 recognizes human CD142, also known as Tissue Factor, is the membrane receptor for coagulation factors VII and VIIa and is the cell surface initiator of coagulation.

This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD142
Applications Flow Cytometry, Immunohistochemistry (Frozen), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone TF9-10H10
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1M mannitol and <0.1% sodium azide
Gene F3
Gene Accession No. P13726
Gene Alias AA409063; CD142; Cf3; Cf-3; Coagulation factor III; coagulation factor III (thromboplastin, tissue factor); coagulation factor III, tissue factor; F3; TF; TFA; Thromboplastin; Tissue factor
Gene Symbols F3
Host Species Mouse
Immunogen denatured tissue factor isolated from human brain by the Factor VII affinity method.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2152
Target Species Human, Monkey
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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