CD146 Mouse anti-Human, PE, Clone: P1H12, BD

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
BDB561013	BD Biosciences 561013	25 Tests
BDB550315	BD Biosciences 550315	100 Tests

Description

The P1H12 monoclonal antibody specifically binds to CD146. CD146 is a 118 kDa transmembrane glycoprotein also known as MCAM, MUC18, or Mel-CAM. CD146 is a member of the immunoglobulin superfamily and is expressed by angioblasts and mesenchymal stems cells and is strongly expressed by blood vessel endothelium and smooth muscle. CD146 is also expressed by melanoma cells, intermediate trophoblasts and a subpopulation of activated T cells. The P1H12 monoclonal antibody has been reported to block endothelial cell adhesion that is observed very early in embryogenesis. It can be useful in the study of embryologic vasculogenesis. This antibody is suitable for immunohistochemical staining of acetone-fixed frozen tissue sections, immunoprecipitation and ELISA.

Specifications

• Antigen: CD146
• Applications: Flow Cytometry
• Conjugate: PE
• Regulatory Status: RUO
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Isotype: IgG1 κ
• Purification Method: Affinity Purified

• Clone: P1H12
• Classification: Monoclonal
• Host Species: Mouse
• Target Species: Human
• Immunogen: Human Umbilical Vein Cells
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

For Research Use Only.