Invitrogen™ CD148 Monoclonal Antibody (10)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA531139

Catalog No. PIMA531139

Description

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human DEP1/PTPRJ.

CD148 is a highly glycosylated transmembrane protein of up to 250 kDa, containing eight fibronectin type III domains in the extracellular region and one tyrosine phosphatase domain in the cytoplasmic region. Expression is found broadly on fibroblasts, epithelial cells, lymphocytes (B, T and NK cells), and myeloid cells (monocytes and granulocytes). CD148 can dephosphorylate proteins such as LAT and PLC-gamma, and is involved in the downregulation of T cell activation. Conversely, CD148 expression can be upregulated following T cell activation.

Specifications

• Antigen: CD148
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: Q12913
• Gene Symbols: PTPRJ
• Immunogen: Recombinant Human DEP1/PTPRJ Protein (Arg997-Ala1337).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA
• Clone: 10
• Conjugate: Unconjugated
• Gene: PTPRJ
• Gene Alias: AI450271; BET; Byp; CD148; CD148 antigen; colon tumor susceptibility 1; density enhanced phosphatase-1; density-enhanced phosphatase 1; DEP1; DEP-1; HPTP beta-like tyrosine phosphatase; HPTP eta; HPTPeta; human density enhanced phosphatase-1; protein tyrosine phosphatase, receptor type J; protein tyrosine phosphatase, receptor type, J; protein tyrosine phosphatase, receptor type, J polypeptide; protein-tyrosine phosphatase eta; Protein-tyrosine phosphatase receptor type J; Ptpb2; PTPbeta2; Ptprj; Receptor-type tyrosine-protein phosphatase eta; R-PTP-ETA; RPTPJ; R-PTP-J; Scc1; Scc-1; Susceptibility to colon cancer 1; susceptibility to colon cancer 1, mouse, homolog of
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 5795
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid