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Invitrogen™ CD15 Chimeric Recombinant Rabbit Monoclonal Antibody (BRA-4F1)
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Catalog No. PIMA548266
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200 μg
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Catalog No. Quantity
PIMA548266 200 μg
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Catalog No. PIMA548266 Supplier Invitrogen™ Supplier No. MA548266
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Description

Rabbit Recombinant Monoclonal Antibody

Specificity: This antibody is specific for CD15. It also shows crossreactivity with the CD15 antigen from other species.

CD15 (Lewis X, Le(x); stage specific embryonic antigen-1, SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins and proteoglycans of various cell types, e.g. granulocytes, mast cells, monocytes, macrophages, cells of gastric mucosa, nervous system or various tumour cells. There are several variants of Lewis x, such as sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation, based on calcium-dependent Le(x)-Le(x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le(x) and its isomer sialyl-Le(a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of Hodgkin's disease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD15 Chimeric
Applications Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Immunocytochemistry
Classification Recombinant Monoclonal
Clone BRA-4F1
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% ProClin 300
Gene FUT4
Gene Accession No. P22083
Gene Alias FUTIV; Lewis X; SSEA-1
Gene Symbols FUT4
Host Species Rabbit
Immunogen This antibody was raised by immunzing mice with human CD15.
Purification Method Protein A
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2526
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG κ
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