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Invitrogen™ CD15 Monoclonal Antibody (MMA)
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Catalog No. PIMA125911
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PIMA125911 1 mL
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Catalog No. PIMA125911 Supplier Invitrogen™ Supplier No. MA125911
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Description

Mouse Monoclonal Antibody

Recommended positive controls: Tonsil.

CD15 (Lewis X, Le(x); stage specific embryonic antigen-1, SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins and proteoglycans of various cell types, e.g. granulocytes, mast cells, monocytes, macrophages, cells of gastric mucosa, nervous system or various tumour cells. There are several variants of Lewis x, such as sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation, based on calcium-dependent Le(x)-Le(x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le(x) and its isomer sialyl-Le(a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of Hodgkin's disease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD15
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone MMA
Conjugate Unconjugated
Formulation Tissue culture supernatant with 0.09% sodium azide
Gene FUT4
Gene Accession No. P22083
Gene Alias FUTIV; Lewis X; SSEA-1
Gene Symbols FUT4
Host Species Mouse
Immunogen U937 histiocytic cell line.
Purification Method IgM
Quantity 1 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2526
Target Species Human
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgM
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