Invitrogen™ CD15 Polyclonal Antibody

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIPA5119027	Invitrogen™ PA5119027	200 μL
PIPA5121974	Invitrogen™ PA5121974	20 μL

Description

CD15 Polyclonal Antibody for Western Blot, IHC (P)

CD15 (Lewis X, Le(x); stage specific embryonic antigen-1, SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins and proteoglycans of various cell types, e.g. granulocytes, mast cells, monocytes, macrophages, cells of gastric mucosa, nervous system or various tumour cells. There are several variants of Lewis x, such as sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation, based on calcium-dependent Le(x)-Le(x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le(x) and its isomer sialyl-Le(a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of Hodgkin's disease.

Specifications

• Antigen: CD15
• Content And Storage: -20°C
• Classification: Polyclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Mouse
• Gene: FUT4
• Gene Alias: FUTIV; Lewis X; SSEA-1
• Gene Symbols: FUT4
• Primary or Secondary: Primary
• Purification Method: Antigen affinity chromatography

• Concentration: 0.87 mg/mL
• Applications: Immunohistochemistry (Paraffin), Western Blot, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300
• Gene Accession No.: Q11127
• Gene ID (Entrez): 14345
• Immunogen: Recombinant protein Cluster Of Differentiation 15. The antigen corresponds to amino acid range 144-389 of the target protein.
• Product Type: Antibody