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CD150 Monoclonal Antibody (mShad150), APC-eFluor™ 780, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
Specifications
| Antigen | CD150 |
|---|---|
| Clone | mShad150 |
| Concentration | 0.2 mg/mL |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
47-150-282
|
Invitrogen
47150282 |
100 μg |
Each of 1 for $341.00
|
N/A | |||||
Description
CD150 (SLAM, Signaling Lymphocyte Activation Molecule) belongs to the immunoglobulin gene superfamily, and is involved in T cell stimulation. SLAM is constitutively expressed on peripheral blood memory T cells, T cell clones, immature thymocytes, and a proportion of B cells, and is rapidly induced on naive T cells after activation. Activated B cells express the membrane bound form, the soluble form and the cytoplasmic isoforms of SLAM. It is suggested that signalling through homophilic SLAM-SLAM binding during B to B and B to T cell interactions enhances the expansion and differentiation of activated B cells. Reports suggest that the extracellular domain of CD150 is the receptor for the measles virus and acts as a co-activator on T cells and B cells. Moreover, CD150 is thought to interact with SH2D1A and with PTPN11 via its cytoplasmic domain. Mutations CD150 gene may be associated with X-linked lympho-proliferative disease (XLP).Specifications
| CD150 | |
| 0.2 mg/mL | |
| Monoclonal | |
| Liquid | |
| RUO | |
| PBS with 0.09% sodium azide; pH 7.2 | |
| 27218 | |
| IgG2b λ | |
| Affinity chromatography | |
| Slamf1 |
| mShad150 | |
| Flow Cytometry | |
| APC-eFluor 780 | |
| Rat | |
| Mouse | |
| Q9QUM4 | |
| Slamf1 | |
| Primary | |
| Antibody |
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