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CD161a Mouse anti-Rat, FITC, Clone: 10/78, BD

Mouse Monoclonal Antibody

$112.00 - $436.00

Specifications

Antigen CD161a
Clone Oct-78
Concentration 0.5mg/mL
Applications Flow Cytometry
Classification Monoclonal
View More Specs

Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
BDB561781
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BD Biosciences
561781
50 μg
Each for $112.00
Add to Cart
 
BDB555008
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BD Biosciences
555008
0.5 mg
Each for $436.00
Add to Cart
 
Description

Description

The 10/78 antibody reacts with NKR-P1A, a 60-kDa homodimer expressed on all natural killer (NK) cells and a small subset of T lymphocytes. The 10/78 antibody competes with the previously described 3.2.3 antibody for binding to the antigen. NKR-P1A is a type-II integral membrane protein with an extracellular C-type lectin domain, which is an NK cell-activating receptor specific for tumor target cells. Many rat dendritic cells have been shown to express NKR-P1A, and a subpopulation of these cells has cytotoxic activity. NKR-P1A has also been detected at low levels on peripheral blood monocytes, and its expression is upregulated in IFN-γ-activated monocytes, specifically in a subpopulation of large monocytes with phagocytic capacity. Furthermore, activated peripheral blood neutrophils may express a low level of NKR-P1A. In the mouse and rat, three members of the NKR-P1 gene family have been identified; but in the human gene family, a single NKR-P1 homologue has been discovered and designated Cd161

Specifications

Specifications

CD161a
0.5mg/mL
Monoclonal
Mouse
Rat
Not reported
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Oct-78
Flow Cytometry
FITC
RUO
Aqueous buffered solution containing ≤0.09% sodium azide.
IgG1 κ
Affinity Purified
NKR-P1A
SDS
Documents

Documents

Product Certifications

For Research Use Only.

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