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  6. Invitrogen™ CD166 (ALCAM) Monoclonal Antibody (eBioALC48), APC, eBioscience™, Invitrogen™ 

Invitrogen™ CD166 (ALCAM) Monoclonal Antibody (eBioALC48), APC, eBioscience™, Invitrogen™

Catalog No. 501123088
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50-112-3088 25 μg
50-112-3089 100 μg
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Catalog No. 50-112-3088 Supplier Invitrogen™ Supplier No. 17166180
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Description

Rat Monoclonal Antibody

Description: Activated leukocyte cell adhesion molecule (ALCAM; CD166) is a 105 kD cell-surface adhesion molecule belonging to the Ig superfamily of receptors. ALCAM is a type I transmembrane glycoprotein, possessing five extracellular Ig domains, a transmembrane domain, and a short cytoplasmic tail. ALCAM is involved in homotypic adhesion, as well as heterotypic adhesion with its natural ligand, CD6. A soluble isoform of ALCAM has been shown to inhibit homophilic adhesive interactions. ALCAM is expressed on a variety of cell types, including activated T and B cells, monocyte-derived dendritic cells, and thymic epithelial cells. ALCAM expression has also been used as a marker for the isolation of pluripotent stem cells. Applications Reported: This eBioALC48 antibody has been reported for use in flow cytometric analysis. Applications Tested: This eBioALC48 antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser. Filtration: 0.2 μm post-manufacturing filtered.

This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD166 (ALCAM)
Applications Flow Cytometry
Classification Monoclonal
Clone eBioALC48
Concentration 0.2 mg/mL
Conjugate APC
Formulation PBS with 0.09% sodium azide; pH 7.2
Gene ALCAM
Gene Accession No. Q61490
Gene Alias activated leukocyte cell adhesion molecule; AI853494; ALCAM; BEN; CD166; CD166 antigen; cell adhesion molecule; DM-GRASP; FLJ38514; HB2; KG-CAM; MEMD; MGC71733; MuSC; Protein DM-GRASP; Protein MEMD; SB-10 antigen; SC1; unnamed protein product
Gene Symbols ALCAM
Host Species Rat
Purification Method Affinity chromatography
Quantity 25 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11658
Target Species Mouse
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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For Research Use Only.

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