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Invitrogen™ CD166 (ALCAM) Monoclonal Antibody (eBioALC48), eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Supplier:  Invitrogen™ 14166137

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Catalog No. 14-166-137


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Description

Description

Activated leukocyte cell adhesion molecule (ALCAM; CD166) is a 105 kD cell-surface adhesion molecule belonging to the Ig superfamily of receptors. ALCAM is a type I transmembrane glycoprotein, possessing five extracellular Ig domains, a transmembrane domain, and a short cytoplasmic tail. ALCAM is involved in homotypic adhesion, as well as heterotypic adhesion with its natural ligand, CD6. A soluble isoform of ALCAM has been shown to inhibit homophilic adhesive interactions. ALCAM is expressed on a variety of cell types, including activated T and B cells, monocyte-derived dendritic cells, and thymic epithelial cells. ALCAM expression has also been used as a marker for the isolation of pluripotent stem cells.

This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD166 (ALCAM)
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
Q61490
ALCAM
Affinity chromatography
RUO
11658
4°C
Liquid
Flow Cytometry, Immunohistochemistry (Paraffin)
eBioALC48
Unconjugated
ALCAM
activated leukocyte cell adhesion molecule; AI853494; ALCAM; BEN; CD166; CD166 antigen; cell adhesion molecule; DM-GRASP; FLJ38514; HB2; KG-CAM; MEMD; MGC71733; MuSC; Protein DM-GRASP; Protein MEMD; SB-10 antigen; SC1; unnamed protein product
Rat
2 mg
Primary
Mouse
Antibody
IgG2a κ
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