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Invitrogen™ CD177 Monoclonal Antibody (MEM-166)
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA119250
Description
This antibody reacts with CD177 (Neutrophil specific antigen 1), a 60 kDa GPI-linked cell surface glycoprotein of uPAR family, expressed on granulocytes and in bone marrow early erythroblasts, megakaryocytes, promyelocytes and myelocytes. Western blot should be performed under non-reducing conditions.
CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils. Its plasma membrane expression is increased during pregnancy and and inflammation or after G-CSF application. Ligand of CD177 has been identified as CD31 (PECAM-1). CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule. The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).
Specifications
CD177 | |
Monoclonal | |
1 mg/mL | |
PBS with 15 mM sodium azide; pH 7.4 | |
Q8N6Q3 | |
CD177 | |
Human granulocytes. | |
100 μg | |
Primary | |
Human, Monkey | |
Antibody | |
IgG1 |
Flow Cytometry, Immunoprecipitation, Western Blot | |
MEM-166 | |
Unconjugated | |
CD177 | |
1190003K14Rik; CD177; CD177 antigen; CD177 molecule; cell surface receptor; HNA2A; HNA-2a; Human neutrophil alloantigen 2a; NB1; NB1 glycoprotein; NB1 GP; Pdp3; Polycythemia rubra vera protein 1; PRV1; PRV-1; RGD1562941; UNQ595/PRO1181 | |
Mouse | |
Protein A | |
RUO | |
57126 | |
4°C, do not freeze | |
Liquid |
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