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Invitrogen™ CD177 Monoclonal Antibody (MEM-166), FITC
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA119597
Description
This antibody reacts with CD177 (Neutrophil specific antigen 1), a 60 kDa GPI-linked cell surface glycoprotein of uPAR family, expressed on granulocytes and in bone marrow early erythroblasts, megakaryocytes, promyelocytes and myelocytes.
CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils. Its plasma membrane expression is increased during pregnancy and and inflammation or after G-CSF application. Ligand of CD177 has been identified as CD31 (PECAM-1). CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule. The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).
Specifications
CD177 | |
Monoclonal | |
FITC | |
CD177 | |
1190003K14Rik; CD177; CD177 antigen; CD177 molecule; cell surface receptor; HNA2A; HNA-2a; Human neutrophil alloantigen 2a; NB1; NB1 glycoprotein; NB1 GP; Pdp3; Polycythemia rubra vera protein 1; PRV1; PRV-1; RGD1562941; UNQ595/PRO1181 | |
Mouse | |
Size-exclusion chromatography | |
RUO | |
57126 | |
4°C, store in dark, DO NOT FREEZE! | |
Liquid |
Flow Cytometry | |
MEM-166 | |
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4 | |
Q8N6Q3 | |
CD177 | |
Human granulocytes. | |
100 Tests | |
Primary | |
Human, Monkey | |
Antibody | |
IgG1 |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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