Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

CD181 (CXCR1) Rat anti-Mouse, PE, Clone: U45-632, BD

Rat Monoclonal Antibody

Manufacturer:  BD Biosciences 566383

Catalog No. BDB566383


Add to cart

Description

Description

The U45-632 monoclonal antibody specifically binds to mouse CD181, also known as C-X-C chemokine receptor type 1 (CXCR1) or IL-8 receptor . CD181 is a chemokine receptor of the G-protein coupled receptor 1 family, also known as seven-transmembrane domain receptors. In the mouse, which is not known to express IL-8 (CXCL8), CD181 binds to mouse GCP-2 (CXCL6). Mouse CD181 can also bind to human IL-8. CD181 is expressed by neutrophils, which are activated upon ligand binding. The chemokine receptors CXCR1 and CXCR2 play an important role in mediating neutrophil recruitment and neutrophil-dependent injury in several models of inflammation.

R-phycoerythrin (PE) is an accessory photosynthetic pigment found in red algae. It exists in vitro as a 240-kDa protein with 23 phycoerythrobilin chromophores per molecule. This makes PE one of the brightest fluorochromes for flow cytometry applications, but its photobleaching properties make it unsuitable for fluorescence microscopy.
Specifications

Specifications

CD181 (CXCR1)
0.2mg/mL
Aqueous buffered solution containing ≤0.09% sodium azide.
Il8ra,Cxcr1,C-X-C chemokine receptor type 1, CXC-R1, CXCR-1, IL-8R A
Mouse CD181 Recombinant Protein
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
RUO
Primary
Murine
U45-632
PE
Affinity Purified
Rat
Rat LEW, also known as Lewis IgG2b, κ
50μg
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit