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CD181 (CXCR1) Rat anti-Mouse, PE, Clone: U45-632, BD

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BDB566383 50 μg
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Description

Rat Monoclonal Antibody

The U45-632 monoclonal antibody specifically binds to mouse CD181, also known as C-X-C chemokine receptor type 1 (CXCR1) or IL-8 receptor . CD181 is a chemokine receptor of the G-protein coupled receptor 1 family, also known as seven-transmembrane domain receptors. In the mouse, which is not known to express IL-8 (CXCL8), CD181 binds to mouse GCP-2 (CXCL6). Mouse CD181 can also bind to human IL-8. CD181 is expressed by neutrophils, which are activated upon ligand binding. The chemokine receptors CXCR1 and CXCR2 play an important role in mediating neutrophil recruitment and neutrophil-dependent injury in several models of inflammation.

R-phycoerythrin (PE) is an accessory photosynthetic pigment found in red algae. It exists in vitro as a 240-kDa protein with 23 phycoerythrobilin chromophores per molecule. This makes PE one of the brightest fluorochromes for flow cytometry applications, but its photobleaching properties make it unsuitable for fluorescence microscopy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD181 (CXCR1)
Classification Monoclonal
Clone U45-632
Concentration 0.2mg/mL
Conjugate PE
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Gene Alias Il8ra,Cxcr1,C-X-C chemokine receptor type 1, CXC-R1, CXCR-1, IL-8R A
Host Species Rat
Immunogen Mouse CD181 Recombinant Protein
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2b κ
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