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CD186 (CXCR6) Rat anti-Mouse, PE, Clone: DANID2, eBioscience™ Non-distribution product as customer accommodation.

Rat Monoclonal Antibody

Manufacturer:  eBioscience 12918682

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Catalog No. 12-918-682


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Description

Description

Description: This DANID2 monoclonal antibody recognizes mouse CD186, also known as CXCR6. This DANID2 antibody will work in flow cytometry on both native and paraformaldehyde-fixed cells. Applications Reported: This DANID2 antibody has been reported for use in flow cytometric analysis. Applications Tested: This DANID2 antibody has been tested by flow cytometric analysis of mouse splenocytes. This may be used at less than or equal to 1.0 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser

CD186, also known as CXCR6, is a G protein-coupled chemokine receptor reported to be one of the cellular receptors of HIV and SIV. CD186 is expressed by NKT cells, various subtypes of T cells with activated and memory phenotypes, and some plasma cells. It has been reported that mouse liver NK cells, but not naïve or splenic NK cells, express CD186. The ligand of CD186, CXCL16, is expressed by macrophages, dendritic cells and liver endothelial cells. Being highly expressed on NKT cells, CD186 is often used as a proxy marker of this cell subset.
Specifications

Specifications

CD186 (CXCR6)
Monoclonal
0.2 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
Q9EQ16
Bonzo, STRL33, TYMSTR
Rat
IgG2a, kappa
100 μg
4° C, store in dark, DO NOT FREEZE!
Primary
80901
Flow Cytometry
DANID2
PE
CXCR6
Liquid
CXCR6
Mammalian cell line expressing the full form of CD186
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Documents
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