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MilliporeSigma™ CD19, Mouse, APC, Clone: SJ25C1,

Mouse Monoclonal Antibody

$157.10 - $1360.00

Specifications

Antigen CD19
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Clone SJ25C1
Host Species Mouse
View More Specs

Products 3
Catalog Number Mfr. No. Quantity Conjugate Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Conjugate Price Quantity & Availability  
MABF1644 View Documents MilliporeSigma™
MABF1644
25 tests APC Each for $157.10
Add to cart
 
MABF1645 View Documents MilliporeSigma™
MABF1645
100 tests APC Each for $346.50
Add to cart
 
MABF1646 View Documents MilliporeSigma™
MABF1646
500 tests APC Each for $1,360.00
Add to cart
 
Description

Description

The SJ25C1 antibody reacts with human CD19, a 95kDa glycoprotein which acts as a co-receptor, along with CD21 (CR2), CD81 (TAPA-1) and CD225 (Leu13), in support of the functional B cell receptor (BCR). This complex provides antigen-specific recognition and subsequent activation of B cells to proliferate and differentiate into antibody-secreting cells (plasma cells) or memory B cells, which are crucial for secondary antigen encounter. Upon activation and tyrosine phosphorylation, the CD19 molecule can provide an anchor for cytoplasmic signaling proteins such as GRB2, SOS or PLCG2. CD19 is a lineage-differentiation marker, as its expression is detectable at the earliest B cell stages, through development, and is finally lost upon transition to mature plasma cells.pThe SJ25C1 antibody is widely used as a phenotypic marker for CD19 expression on B cells, as well as on dendritic cell subsets.
Specifications

Specifications

CD19
Monoclonal
Mouse
Purified mouse monoclonal in buffer containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2.
Stable for 1 year at 2°-8°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
Primary
SJ25C1
Purified
Flow Cytometry
RUO

For Research Use Only. Not for use in diagnostic procedures.

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