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Invitrogen™ CD205 Polyclonal Antibody
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Catalog No. PIPA587607
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PIPA587607 100 μL
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Catalog No. PIPA587607 Supplier Invitrogen™ Supplier No. PA587607
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Description

Rabbit Polyclonal Antibody

Positive Samples: Mouse lung; Cellular Location: Membrane, Single-pass type I membrane protein Immunogen sequence: CEDNWEKNEQ FGSCYQFNTQ TALSWKEAYV SCQNQGADLL SINSAAELTY LKEKEGIAKI FWIGLNQLYS ARGWEWSDHK PLNFLNWDPD RPSAPTIGGS SCARMDAESG LWQSFSCEAQ LPYVCRKPLN NTVELTDVWT YSDTRCDAGW LPNNGFCYLL VNESNSWDKA HAKCKAFSSD LISIHSLADV EVVVTKLHNE DIKEEVWIGL KNINIPTLFQ WSDGTEVTLT YWDENEPNVP YNKTPNCVSY LGELGQWKVQ SCEEKLKYVC KRKGEKLNDA SSDKMC.

CD205 (LY25, Lymphocyte Antigen 75) is an integral membrane glycoprotein involved in antigen uptake, trafficking and presentation that improves the induction of antigen-specific T cell immunity. CD205 is highly expressed by CD8+ dendritic cells (DCs) and also expressed at different levels by bone marrow Gr1+ cells, Langerhans cells, (BMDC) bone marrow derived DCs and thymic epithelial cells. CD205 acts as an endocytic receptor that directs captured antigens to the extracellular space towards a specialized antigen processing region. Further, CD205 also prompts the reduced proliferation of B lymphocytes. Diseases associated with CD205 dysfunction include pneumonic plague and lipid pneumonia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD205
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.38 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene LY75
Gene Accession No. O60449, Q60767
Gene Alias CA-IX; CD205; CLEC13B; C-type lectin domain family 13 member B; DCL-1 fusion; DEC205; DEC-205; DEC-205/CD205 protein; gp200; gp200-MR6; group VI C-type animal lectin; LY75; ly-75; Lymphocyte antigen 75; membrane antigen MN; P54/58N; pMW1; RGD1565962; RP23-10L17.4
Gene Symbols LY75
Host Species Rabbit
Immunogen Recombinant protein (or fragment).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17076, 4065
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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