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CD22 Mouse anti-Human, FITC, Clone: HIB22, BD

Catalog No. p-7092480 Shop All BD Biosciences Products
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BDB561771 25 Tests
BDB555424 100 Tests
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Catalog No. BDB561771 Supplier BD Biosciences Supplier No. 561771
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Description

Mouse Monoclonal Antibody

The HIB22 monoclonal antibody specifically binds to CD22. CD22 is a 130-140 kDa glycosylated type I integral membrane protein present on the surface of mature B cells. CD22 is expressed in the cytoplasm of virtually all B cells except plasma cells. CD45RO antigen on T cells and CD75 antigen on B cells have been identified as ligands for CD22. CD22 has been reported to participate in B-cell activation and also as an adhesion molecule. Although the immunobiology of this antigen has not been fully elucidated, reports indicate that ligation of CD22 induces constitutive internalization of the molecule followed by complete degradation.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD22
Applications Flow Cytometry
Classification Monoclonal
Clone HIB22
Conjugate FITC
Description BL-CAM; Siglec-2; Bgp135; Lyb8; LPAP
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Purification Method Affinity Purified
Quantity 25 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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For Research Use Only.

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