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Invitrogen™ CD229 Monoclonal Antibody (HLy 9.1.25), PE
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Catalog No. 01672437
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100 Tests
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01672437 100 Tests
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Catalog No. 01672437 Supplier Invitrogen™ Supplier No. MA135946
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Description

Mouse Monoclonal Antibody

CD229 (Ly9) is a cell surface receptor of the CD150 family, which includes also e.g. CD48 and CD224. Receptors of this family regulate cytokine production and cytotoxicity of lymphocytes and NK cells. High levels of CD229 are found on T and B cells, where its expression increases during their maturation. It is absent on granulocytes, bone marrow-derived dendritic cells, platelets and erythrocytes. CD229 has been also reported on mouse monocytes and NK cells. CD229 interacts homophilically through its N-terminal domain and localizes to the contact site between T cells and antigen presenting B cells during antigen-dependent immune synapse formation.

CD229 (Ly9) is a cell surface receptor of the CD150 family, which includes also e.g. CD48 and CD224. Receptors of this family regulate cytokine production and cytotoxicity of lymphocytes and NK cells. High levels of CD229 are found on T and B cells, where its expression increases during their maturation. It is absent on granulocytes, bone marrow-derived dendritic cells, platelets and erythrocytes. CD229 has been also reported on mouse monocytes and NK cells. CD229 interacts homophilically through its N-terminal domain and localizes to the contact site between T cells and antigen presenting B cells during antigen-dependent immune synapse formation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD229
Applications Flow Cytometry
Classification Monoclonal
Clone HLy 9.1.25
Conjugate PE
Formulation PBS with 15mM sodium azide
Gene Ly9
Gene Accession No. Q01965, Q9HBG7
Gene Alias AI893573; CD229; CDABP0070; Cell surface molecule Ly-9; hly9; Lgp100; LY9; Ly-9; Lymphocyte antigen 9; mLY9; RP11-312J18.1; Signaling lymphocytic activation molecule 3; SLAM family member 3; SLAMF3; T100; T-lymphocyte surface antigen Ly-9
Gene Symbols Ly9
Host Species Mouse
Immunogen Mouse pre-B cell line 300.19 transfected with CD229 cDNA.
Purification Method Purified
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17085, 4063
Target Species Human, Mouse
Content And Storage 4°C, store in dark
Product Type Antibody
Form Liquid
Isotype IgG1
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