Invitrogen™ CD298 Recombinant Rabbit Monoclonal Antibody (0B7M7)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA537934

Catalog No. PIMA537934

Description

Positive Samples: 293T, U-87MG, Mouse lung, Mouse testis, Mouse brain, Rat lung, Rat testis, Rat spleen Immunogen sequence: GLKPEGVPRI DCVSKNEDIP NVAVYPHNGM IDLKYFPYYG KKLHVGYLQP LVAVQVSFAP NNTGKEVTVE CKIDGSANLK SQDDRDKFLG RVMFKITARA.

The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. This gene encodes a beta 3 subunit. A pseudogene exists for this gene, and it is located on chromosome 2.

Specifications

• Antigen: CD298
• Classification: Recombinant Monoclonal
• Concentration: 0.45 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P54709, P97370, Q63377
• Gene Symbols: ATP1B3
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 180-279 of human ATP1B3 (P54709).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Clone: 0B7M7
• Conjugate: Unconjugated
• Gene: ATP1B3
• Gene Alias: AA409958; AI664000; Atp1b3; ATPase Na+/K+ transporting subunit beta 3; ATPase, Na+/K+ beta 3 polypeptide; ATPase, Na+/K+ transporting, beta 3 polypeptide; ATPase, Na+K+ transporting, beta polypeptide 3; ATPB-3; AW212096; CD298; CD298 antigen; Na K-ATPase beta-3 subunit; Na+/K+ -ATPase beta 3 subunit; NKAB3S; Sodium Potassium ATPase; Sodium/potassium-dependent ATPase subunit beta-3; sodium/potassium-transporting ATPase subunit beta-3
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11933, 25390, 483
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid