CD3 delta Mouse anti-Human, Mouse, Clone: 3A12H2, Proteintech

Mouse Monoclonal Antibody

Supplier:  Proteintech Group Inc 601941IG150UL

Catalog No. 50-173-6297

Description

The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.

Specifications

• Antigen: CD3 delta
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P04234, P04235
• Gene Symbols: Cd3d
• Immunogen: CD3 delta Fusion Protein Ag10207
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: 3A12H2
• Conjugate: Unconjugated
• Gene: CD3D
• Gene Alias: CD3 delta, CD3D, CD3-delta, T cell receptor T3 delta chain, T3D
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 12500, 915
• Content And Storage: -20°C
• Form: Liquid