CD30 (Reed-Sternberg Cell Marker) Ab-4 Mouse Monoclonal Antibody, Epredia™

Ensure accurate, reproducible results in immunohistochemistry experiments with Epredia™ CD30 (Reed-Sternberg Cell Marker) Ab-4, Mouse Monoclonal Antibody.

Catalog Number	Mfr. No.	Form	Quantity
MS1857P1	Epredia MS1857P1	Concentrated	500 μL
MS1857P	Epredia MS1857P	Concentrated	1 mL
MS1857R7	Epredia MS1857R7	Prediluted	7 mL
MS1857P0	Epredia MS1857P0	Concentrated	100 μL

Description

CD30, a single chain glycoprotein, is synthesized as a 90 kDa precursor which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. The CD30/Ki-1 antigen is expressed by mononuclear Hodgkin and multinucleated Reed-Sternberg cells in Hodgkin's disease, by the tumor cells of a majority of anaplastic large cell lymphomas, and by a varying proportion of activated T and B cells. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).

Host Species: Mouse

Clone: HRS4

Isotype: IgG1

Species Reactivity: Human. Others not known.

Epitope: Extracellular domain

Immunogen: Recombinant extracellular domain of CD30 protein

Molecular Weight: 120 kDa (mature), 95 kDa (precursor)

Positive Control: Hodgkin's lymphoma

Cellular Localization: Membrane

Recommended for:

• Immunohistochemistry (Formalin/paraffin)

Specifications

• Antigen: CD30 Ab-4
• Applications: Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Regulatory Status: IVD
• Target Species: Human
• Isotype: IgG1

• Clone: HRS4
• Classification: Monoclonal
• Host Species: Mouse
• Research Discipline: Oncogenesis
• Immunogen: Recombinant extracellular domain of CD30 protein
• Primary or Secondary: Primary