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Invitrogen™ CD300b Polyclonal Antibody
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Catalog No. PIPA5120746
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100 μL
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PIPA5120746 100 μL
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Catalog No. PIPA5120746 Supplier Invitrogen™ Supplier No. PA5120746
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Description

Rabbit Polyclonal Antibody

Positive test controls include: Mouse lung, Rat lung. Immunogen sequence: MWLPPALLLL SLSGCFSIQG PESVRAPEQG SLTVQCHYKQ GWETYIKWWC RGVRWDTCKI LIETRGSEQG EKSDRVSIKD NQKDRTFTVT MEGLRRDDAD VYWCGIERRG PDLGTQVKVI VDPEGAASTT ASSPTNSNMA VFIGSHKRNH YMLLVFVKVP ILLILVTAIL WLKGSQRVPE EPGEQPIYMN FSEPLTKDMA T.

CD300 molecule-like family member b (CD300LB), also known as CLM-7, is a gene located on chromosome 17q25.1, encoding an immunoreceptor that belongs to the CD300 family of molecules. CD300LB is primarily expressed on the surface of myeloid cells, including dendritic cells and macrophages, where it plays an essential role in modulating immune responses. The receptor is involved in the regulation of cell activation and inflammatory responses through its interactions with phosphatidylserine and other lipid ligands, which can lead to either activation or inhibition of immune cell functions. CD300LB influences processes like antigen presentation, phagocytosis, and cytokine production, thereby impacting innate immune responses and the maintenance of immune homeostasis. Its expression and activity are of particular interest in contexts like autoimmunity, infection, and cancer, where it may contribute to disease progression and serve as a potential therapeutic target in modulating immune functions.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD300b
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.95 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene CD300LB
Gene Accession No. A8K4G0, Q3U497
Gene Alias CD300 antigen like family member B; CD300 antigen-like family member B; CD300 molecule like family member b; CD300 molecule-like family member b; CD300b; CD300LB; CLM7; CLM-7; CMRF35A2; CMRF35-A2; CMRF35-like molecule 7; CMRF-35-like molecule-7; Gm253; Immune receptor expressed on myeloid cells 3; IREM3; IREM-3; Leukocyte mono-Ig-like receptor 5; LMIR5; TREM5; TREM-5; triggering receptor expressed on myeloid cells 5; UNQ2530/PRO6029
Gene Symbols CD300LB
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-201 of human CD300LB (NP_777552.3).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 124599, 217304, 501738
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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