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Invitrogen™ CD31 Monoclonal Antibody (MBC78.2), FITC
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Catalog No. MHCD3101
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500 μL
2 mL
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Catalog No. Quantity
MHCD3101 500 μL
MHCD31014 2 mL
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Catalog No. MHCD3101 Supplier Invitrogen™ Supplier No. MHCD3101
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Description

Mouse Monoclonal Antibody

Commonly used, FITC conjugates provide relatively high absorptivity, excellent fluorescence quantum yield, and good water solubility.

CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD31
Applications Flow Cytometry
Classification Monoclonal
Clone MBC78.2
Conjugate FITC
Formulation PBS with 4mg/mL BSA and 0.1% sodium azide
Gene Pecam1
Gene Accession No. P16284
Gene Alias C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule
Gene Symbols Pecam1
Host Species Mouse
Immunogen Human CD31.
Purification Method Purified
Quantity 500 μL
Regulatory Status ASR
Primary or Secondary Primary
Gene ID (Entrez) 5175
Target Species Human
Content And Storage 4°C, store in dark
Product Type Antibody
Form Liquid
Isotype IgG1
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