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  6. Invitrogen™ CD357 (AITR/GITR) Monoclonal Antibody (DTA-1), APC-eFluor™ 780, eBioscience™, Invitrogen™ 

Invitrogen™ CD357 (AITR/GITR) Monoclonal Antibody (DTA-1), APC-eFluor™ 780, eBioscience™, Invitrogen™
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Catalog No. 47587482
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47-587-482 100 μg
47-587-480 25 μg
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Catalog No. 47-587-482 Supplier Invitrogen™ Supplier No. 47587482
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Description

Rat Monoclonal Antibody

Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), also called GITR or AITR is a protein that in humans is encoded by the TNFRSF18 gene. It is mapped to 1p36.33. This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25 (+)CD4 (+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
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Specifications

Antigen CD357 (AITR/GITR)
Applications Flow Cytometry
Classification Monoclonal
Clone DTA-1
Concentration 0.2 mg/mL
Conjugate APC-eFluor 780
Formulation PBS with 0.09% sodium azide; pH 7.2
Gene Tnfrsf18
Gene Accession No. O35714
Gene Alias Activation-inducible TNFR family receptor; AITR; CD357; GITR; GITR-D; glucocorticoid-induced TNFR-related protein; PRO364; TNF receptor superfamily activation-inducible protein; TNF receptor superfamily member 18; TNFRSF18; Tumor necrosis factor receptor superfamily member 18; tumor necrosis factor receptor superfamily, member 18; UNQ319; UNQ319/PRO364
Gene Symbols Tnfrsf18
Host Species Rat
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21936
Target Species Mouse
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG2b κ
Product Line eBioscience
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