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  6. Invitrogen™ CD39 Monoclonal Antibody (eBioA1 (A1)), Super Bright™ 702, eBioscience™, Invitrogen™ 

Invitrogen™ CD39 Monoclonal Antibody (eBioA1 (A1)), Super Bright™ 702, eBioscience™, Invitrogen™
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Catalog No. 67039942
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Catalog No. 67-039-942 Supplier Invitrogen™ Supplier No. 67039942
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Description

Mouse Monoclonal Antibody

The eBioA1 monoclonal antibody reacts with human CD39 also known as ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1) or NTPDase. CD39 is an integral membrane protein with two transmembrane domains and exists as a homotetramer. It is the most prom

CD39 is an integral membrane protein characterized by two transmembrane domains and forms a homotetramer structure. It is recognized as the most prominent ectoenzyme within the immune system, primarily functioning to remove toxic extracellular ATP by converting it into ADP or AMP. CD39 works in conjunction with CD73 to hydrolyze ATP and is well characterized on Langerhans cells. Originally identified on activated lymphocytes, CD39 is expressed on a variety of immune cells, including peripheral blood B cells, monocytes, and T cell clones. It is also found on a subset of T cells, B cells, and dendritic cells, with weaker expression observed on monocytes and granulocytes. The CD39 cell surface antigen is a 70-100kD molecule, and its expression is induced on T cells and increases on B cells as a late activation antigen. CD39 possesses intrinsic ecto-ATPase activity, playing a crucial role in modulating extracellular nucleotide levels and contributing to immune regulation.
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Specifications

Antigen CD39
Applications Flow Cytometry
Classification Monoclonal
Clone eBioA1 (A1)
Concentration 5 μL/Test
Conjugate Super Bright 702
Formulation PBS with BSA and 0.09% sodium azide; pH 7.2
Gene ENTPD1
Gene Accession No. P49961
Gene Alias 2610206B08Rik; AA408691; ATPDase; Cd39; CD39 antigen; DKFZp686D194; DKFZp686I093; ecto-apyrase; Ecto-ATP diphosphohydrolase 1; ecto-ATPase 1; ecto-ATPDase 1; Ectonucleoside triphosphate diphosphohydrolase 1; ENTPD1; FLJ40921; FLJ40959; Lymphoid cell activation antigen; NTPDase 1; NTPDase-1; SPG64
Gene Symbols ENTPD1
Host Species Mouse
Purification Method Affinity chromatography
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 953
Target Species Human
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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