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Invitrogen™ CD4/CD26 Antibody Cocktail, FITC, PE
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Catalog No. 01670837
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01-670-837 100 Tests
01-670-838 50 Tests
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Catalog No. 01-670-837 Supplier Invitrogen™ Supplier No. MA112118
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Description

Antibody Cocktail

This antibody is a monoclonal mixture of FITC-conjugated CD4 (clone 7E14, isotype IgG1) and PE-conjugated CD26 (clone EUG-6, isotype IgG2a).

The CD4 antigen is involved in the recognition of the type II MHC antigen. It is also a receptor for HIV. It is present on most T helper cells and normal thymocytes. The cytoplasmic portion of CD4 is associated with p56lck tyrosine kinase. CD4 expression is commonly found in human lymph nodes and tonsils. CD26 [also known as dipeptidyl peptidase IV (DPP IV), adenosine deaminase (ADA) binding protein]. 1 - 3 is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Cross-linking of CD26 using this antibody dramatically enhances the anti CD3-induced IL - 2 production.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD4/CD26
Applications Flow Cytometry
Classification Cocktail
Clone 7E14, EUG-6, EUG-6
Conjugate FITC/PE
Formulation PBS with 0.2% carrier protein and 0.08% sodium azide
Gene CD4
Gene Accession No. P01730, P27487
Gene Alias ADABP; ADCP2; ADCP-2; Adenosine deaminase complexing protein 2; CD26; CD4; CD4 antigen (p55); CD4 antigen p55; CD4 molecule; CD4 receptor; CD4mut; dipeptidyl peptidase 4; Dipeptidyl peptidase 4 membrane form; Dipeptidyl peptidase 4 soluble form; Dipeptidyl peptidase IV; Dipeptidyl peptidase IV membrane form; Dipeptidyl peptidase IV soluble form; dipeptidylpeptidase 4; dipeptidyl-peptidase 4; dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2); DPP IV; DPP4; DPPIV; DPP-IV; T-cell activation antigen CD26; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; TP103
Gene Symbols CD4, DPP4
Host Species Mouse
Immunogen human peripheral blood T lymphocytes.
Purification Method Protein A/G
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1803, 920
Target Species Human
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG1, IgG2a
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Safety and Handling

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