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CD4/CD27 Antibody Cocktail, FITC, PE, Invitrogen™

Catalog No. 01670840
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Catalog No. Quantity
01-670-840 50 Tests
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Catalog No. 01-670-840 Supplier Thermo Scientific Supplier No. MA112121

Description

Antibody Cocktail

This antibody is a monoclonal mixture of FITC-conjugated CD4 (clone 7E14, isotype IgG1) and PE-conjugated CD27 (clone DEN-3, isotype IgG1).

The CD4 antigen is involved in the recognition of the type II MHC antigen. It is also a receptor for HIV. It is present on most T helper cells and normal thymocytes. The cytoplasmic portion of CD4 is associated with p56lck tyrosine kinase. CD4 expression is commonly found in human lymph nodes and tonsils. CD27 (50 kDa) is a member of the tumor necrosis factor (TNF) receptor superfamily. CD40 and CD30 are also members of the TNF receptor superfamily. The TNF superfamily members are known for the regulation of cell proliferation and death. In contrast to the expression of other TNFR/TNF family members, expression of CD27 and its ligand CD70 is predominantly confined to lymphocytes. High expression levels of CD27 appear to be dependent on proper ligation of antigen receptors. CD70 expression requires additional co-stimulatory and/or pro-inflammatory signals. CD27 is a membranebound receptor, but a soluble form of CD27 is also produced.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD4/CD27
Applications Flow Cytometry
Classification Cocktail
Clone 7E14, DEN-3, DEN-3
Conjugate PE
Formulation PBS with 0.2% carrier protein and 0.08% sodium azide
Gene CD27
Gene Accession No. P01730, P26842
Gene Alias CD27; CD27 antigen; CD27 molecule; CD27L receptor; CD4; CD4 antigen (p55); CD4 antigen p55; CD4 molecule; CD4 receptor; CD4mut; S152; S152. LPFS2; sCD27; soluble CD27; T cell activation antigen S152; T14; T-cell activation antigen CD27; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; TNFRSF7; Tp55; Tumor necrosis factor receptor superfamily member 7; tumor necrosis factor receptor superfamily, member 7
Gene Symbols CD27, CD4
Host Species Mouse
Immunogen human peripheral blood T lymphocytes
Purification Method Protein A/G
Quantity 50 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 920, 939
Target Species Human
Content And Storage 4° C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG1
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