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Invitrogen™ CD4/CD28 Antibody Cocktail, FITC, PE
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Catalog No. p-7170515
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01-670-841 100 Tests
01-670-842 50 Tests
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Catalog No. 01-670-841 Supplier Invitrogen™ Supplier No. MA112122
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Description

Antibody Cocktail

This antibody is a monoclonal mixture of FITC-conjugated CD4 (clone 7E14, isotype IgG1) and PE-conjugated CD28 (clone B-23, isotype IgG1).

The CD4 antigen is involved in the recognition of the type II MHC antigen. It is also a receptor for HIV. It is present on most T helper cells and normal thymocytes. The cytoplasmic portion of CD4 is associated with p56lck tyrosine kinase. CD4 expression is commonly found in human lymph nodes and tonsils. Human CD28 antigen is a 44 kDa disulfide linked homodimeric T cell specific surface glycoprotein. It is a cell adhesion molecule of the immunoglobulin superfamily which is constitutively expressed on most peripheral blood T lymphocytes (approximately 95% of CD4+ cells and 50% of CD8+ cells). Mature thymocytes exhibit higher levels of CD28 than the immature cells. Activation of T cells results in enhanced CD28 expression. T cell activation requires two combined signals provided by antigen presenting cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD4/CD28
Applications Flow Cytometry
Classification Cocktail
Clone 7E14, B-23, B-23
Conjugate FITC/PE
Formulation PBS with 0.2% carrier protein and 0.08% sodium azide
Gene CD28
Gene Accession No. P01730, P10747
Gene Alias CD28; CD28 antigen; CD28 molecule; CD4; CD4 antigen (p55); CD4 antigen p55; CD4 molecule; CD4 receptor; CD4mut; MGC138290; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; T-cell-specific surface glycoprotein CD28; Tp44
Gene Symbols CD28, CD4
Host Species Mouse
Immunogen human peripheral blood T lymphocytes and HPB-ALL T-cell line.
Purification Method Protein A/G
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 920, 940
Target Species Human
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG1
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