CD4 Mouse anti-Human, Alexa Fluor 700, Clone: SK3 (also known as Leu3a), BD

Catalog No.	Quantity
BDB566318	25 Tests

Catalog No. BDB566318 Supplier BD Biosciences Supplier No. 566318

Description

Mouse Monoclonal Antibody

The SK3 monoclonal antibody specifically binds to CD4. The CD4 antigen is a 55 kDa type 1 transmembrane glycoprotein that belongs to the immunoglobulin superfamily. It is expressed on T-helper/inducer lymphocytes and monocytes. CD3+CD4+ T cells comprise approximately 28% to 58% of normal peripheral blood lymphocytes. CD4 is also expressed on 80% to 95% of normal thymocytes. The CD4 antigen is present in low density on the cell surface of monocytes and in the cytoplasm of monocytes and macrophages (CD3-CD4+). CD4 serves as a T cell coreceptor for MHC class II antigen recognition and as a receptor for the human immunodeficiency virus (HIV). The SK3 antibody inhibits HIV binding to CD4+ cells.

Alexa Fluor™ 700 is a far-red dye that can be excited with a 633–640nm laser. This enables multicolor analysis in conjunction with APC or Alexa Fluor™ 647, and APC-H7 or APC-Cy7 reagents.

Specifications

• Antigen: CD4
• Classification: Monoclonal
• Clone: SK3 (also known as Leu3a)
• Conjugate: Alexa Fluor 700
• Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
• Gene Alias: L3T4, Leu3a, T-cell surface antigen T4/Leu-3, W3/25, CD4 antigen (p55)
• Host Species: Mouse
• Immunogen: Human Peripheral Blood T Cells
• Purification Method: Affinity Purified
• Quantity: 25 Tests
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
• Isotype: IgG1 κ