CD4 Mouse anti-Human, Alexa Fluor 700, Clone: SK3 (also known as Leu3a), BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 566318

Catalog No. BDB566318

Description

The SK3 monoclonal antibody specifically binds to CD4. The CD4 antigen is a 55 kDa type 1 transmembrane glycoprotein that belongs to the immunoglobulin superfamily. It is expressed on T-helper/inducer lymphocytes and monocytes. CD3+CD4+ T cells comprise approximately 28% to 58% of normal peripheral blood lymphocytes. CD4 is also expressed on 80% to 95% of normal thymocytes. The CD4 antigen is present in low density on the cell surface of monocytes and in the cytoplasm of monocytes and macrophages (CD3-CD4+). CD4 serves as a T cell coreceptor for MHC class II antigen recognition and as a receptor for the human immunodeficiency virus (HIV). The SK3 antibody inhibits HIV binding to CD4+ cells.

Alexa Fluor™ 700 is a far-red dye that can be excited with a 633–640nm laser. This enables multicolor analysis in conjunction with APC or Alexa Fluor™ 647, and APC-H7 or APC-Cy7 reagents.

Specifications

• Antigen: CD4
• Clone: SK3 (also known as Leu3a)
• Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Target Species: Human
• Isotype: IgG1 κ

• Classification: Monoclonal
• Conjugate: Alexa Fluor 700
• Gene Alias: L3T4, Leu3a, T-cell surface antigen T4/Leu-3, W3/25, CD4 antigen (p55)
• Immunogen: Human Peripheral Blood T Cells
• Quantity: 25 Tests
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.