CD4 Mouse anti-Human, APC-Cy7, Clone: RPA-T4, BD

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
BDB561839	BD Biosciences 561839	25 Tests
BDB557871	BD Biosciences 557871	100 Tests

Description

The RPA-T4 monoclonal antibody specifically binds to CD4, a 59 kDa single-chain transmembrane glycoprotein that is expressed on T-helper/inducer cell populations. CD4 is also expressed on thymocytes subsets and at lower levels on monocytes and macrophages. CD4 functions as a co-receptor in MHC class II-restricted antigen-induced T cell activation and as a receptor for human immunodeficiency viruses (HIV). This antibody binds to the D1 domain (CDR1 and CDR3 epitopes) of the CD4 antigen and reacts with approximately 80% of thymocytes and 45% of peripheral blood lymphocytes. RPA-T4 is capable of blocking HIV-1, gp120, and inhibits syncytium formation.

Specifications

• Antigen: CD4
• Applications: Flow Cytometry
• Conjugate: APC-Cyanine7
• Regulatory Status: RUO
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Clone: RPA-T4
• Classification: Monoclonal
• Host Species: Mouse
• Target Species: Human
• Isotype: IgG1 κ
• Purification Method: Affinity Purified

For Research Use Only.