CD4 Mouse anti-Human, Clone: OTI4A11, lyophilized, TrueMAB™

Catalog No.	Quantity
50-165-9549	100 μg

Catalog No. 50-165-9549 Supplier OriGene Supplier No. CF500479

Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

The CD4 antigen is involved in the recognition of MHC class II molecules and is a co-receptor for HIV. CD4 is primarily expressed in a subset of T-lymphocytes, also referred to as T helper cells, but may also be expressed by other cells in the immune system, such as monocytes, macrophages, and dendritic cells. At the tissue level, CD4 expression may be detected in thymus, lymph nodes, tonsils, and spleen, and also in specific regions of the brain, gut, and other non-lymphoid tissues. CD4 functions to initiate or augment the early phase of T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase, Lck. It may also function as an important mediator of direct neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcripts have been identified in this gene.

Specifications

• Antigen: CD4
• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Classification: Monoclonal
• Clone: OTI4A11
• Conjugate: Unconjugated
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene: CD4
• Gene Accession No.: P01730
• Gene Alias: CD4mut
• Gene Symbols: CD4
• Host Species: Mouse
• Immunogen: Full length human recombit protein of human CD4 produced in HEK293T cell.
• Purification Method: Affinity Chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 920
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG2a